HIV type 1 subtypes in circulation in northern Kenya.

نویسندگان

  • Samoel A Khamadi
  • Washington Ochieng
  • Raphael W Lihana
  • Joyceline Kinyua
  • Joseph Muriuki
  • Joseph Mwangi
  • Raphael Lwembe
  • Michael Kiptoo
  • Saida Osman
  • Nancy Lagat
  • Roger Pelle
  • Anne Muigai
  • Jane Y Carter
  • Isao Oishi
  • Hiroshi Ichimura
  • D L Mwaniki
  • Fredrick A Okoth
  • Solomon Mpoke
  • Elijah M Songok
چکیده

The genetic subtypes of HIV-1 circulating in northern Kenya have not been characterized. Here we report the partial sequencing and analysis of samples collected in the years 2003 and 2004 from 72 HIV-1-positive patients in northern Kenya, which borders Ethiopia, Somalia, and Sudan. From the analysis of partial env sequences, it was determined that 50% were subtype A, 39% subtype C, and 11% subtype D. This shows that in the northern border region of Kenya subtypes A and C are the dominant HIV-1 subtypes in circulation. Ethiopia is dominated mainly by HIV-1 subtype C, which incidentally is the dominant subtype in the town of Moyale, which borders Ethiopia. These results show that cross-border movements play an important role in the circulation of subtypes in Northern Kenya.

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عنوان ژورنال:
  • AIDS research and human retroviruses

دوره 21 9  شماره 

صفحات  -

تاریخ انتشار 2005